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Study identifier: NCT05908214 Synced from ClinicalTrials.gov · July 28, 2026
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The Application of Wide Pulse High Frequency Neuromuscular Electrical Stimulation in Disorders Associated With Motoneuron Hyperexcitability

Condition: Stroke · Cramp · Restless Legs Syndrome  ·  Sponsor: University of Lausanne

PhaseNA
Planned participants110
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

In the present project, the investigators aim at proposing innovative ways of investigating spinal motoneuron hyperexcitability to counteract the associated impairments by using wide pulse high frequency neuromuscular electrical stimulation (WPHF NMES) in various populations. The investigators will use WPHF NMES contractions as a model to gain insights into the mechanisms underlying muscle cramps, restless legs syndrome or stroke-induced spasticity as there is evidence that they share common underlying mechanisms. The investigators will then use WPHF NMES as a training modality to improve plantar flexor neuromuscular function in stroke patients by taking advantage of their motoneuronal hyperexcitability.

This description comes directly from the study's public registry record.

Talk to the study team

Nicolas Place, PhD  ·  +41216923806  ·  nicolas.place@unil.ch

Always discuss trial participation with your own doctor first.

Locations (1)

Bâtiment Synathlon, quartier UNIL-CentreLausanne, SwitzerlandRecruiting

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Source record: clinicaltrials.gov/study/NCT05908214