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Study identifier: NCT05907629 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging

Condition: Stroke · Intracranial Atherosclerotic Stenosis (ICAS)  ·  Sponsor: Yale University

PhaseN/A
Planned participants300
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

CAPTIVA-MRI is an observational multimodal MR imaging study that is ancillary to the CAPTIVA trial \[a 3-arm, double-blind Phase III trial conducted at approximately 115 StrokeNet sites randomizing patients with stroke attributed to 70-99% intracranial atherosclerotic stenosis (ICAS) to aspirin plus ticagrelor, clopidogrel, or rivaroxaban.\] The primary goal of this ancillary study is to determine if MRI biomarkers can potentially identify ICAS patients who fail best medical management. The CAPTIVA-MRI study leverages the CAPTIVA trial design and implementation to capture information that will inform and facilitate the next generation of ICAS trials and the management of patients with ICAS.

This description comes directly from the study's public registry record.

Talk to the study team

Ka-Ho Wong  ·  801-585-7575  ·  ka-ho.wong@hsc.utah.edu

Amy Sulken  ·  sulkenay@ucmail.uc.edu

Always discuss trial participation with your own doctor first.

Locations (28)

University of Alabama HospitalBirmingham, Alabama, United StatesRecruiting
University of Colorado HospitalAurora, Colorado, United StatesNot Yet Recruiting
Hartford HospitalHartford, Connecticut, United StatesNot Yet Recruiting
Yale New Haven HospitalNew Haven, Connecticut, United StatesRecruiting
MedStar Washington Hospital CenterWashington D.C., District of Columbia, United StatesRecruiting
Baptist Medical Center JacksonvilleJacksonville, Florida, United StatesRecruiting
Jackson Memorial Hospital, MiamiMiami, Florida, United StatesRecruiting
Cleveland Clinic Tradition HospitalPort Saint Lucie, Florida, United StatesNot Yet Recruiting
SIH Memorial Hospital of CarbondaleCarbondale, Illinois, United StatesNot Yet Recruiting
University of Illinois HospitalChicago, Illinois, United StatesRecruiting
University of Chicago Medical CenterChicago, Illinois, United StatesRecruiting
Metro Health HospitalWyoming, Michigan, United StatesNot Yet Recruiting

+ 16 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05907629