← Eichor
Study identifier: NCT05906511 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

PK/PD of Oral and Vaporized Delta-9-Tetrahydrocannabinol (THC) in Older Adults

Condition: Pain, Tolerance · Oral vs Vaporized THC · Abuse Liability  ·  Sponsor: Yale University

PhaseEARLY_Phase 1
Planned participants20
Who can joinAll sexes, 65 Years to no upper limit
Healthy volunteersYes

About this study

The overarching goal of this double-blind, placebo-controlled, crossover study is to characterize the pharmacokinetic (PK) and pharmacodynamic (PD) effects of the main analgesic and psychoactive constituent of cannabis, delta-9 tetrahydrocannabinol (THC), among older adults - the fastest growing population of cannabis consumers, and the most likely age cohort to use cannabinoids to relieve pain. This protocol includes two sub-studies, each randomizing 20 men and women aged 65 years or older to receive two administration routes of THC; oral administration and vaporized administration.

This description comes directly from the study's public registry record.

Talk to the study team

Julia Meyerovich, M.S.  ·  203-623-7493  ·  julia.meyerovich@yale.edu

Always discuss trial participation with your own doctor first.

Locations (1)

VA Connecticut Healthcare SystemWest Haven, Connecticut, United StatesRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT05906511