Condition: Pregnancy, High Risk · Sponsor: George Washington University
Access to quality antenatal care (ANC) and postnatal care (PNC), including maternal, newborn, and infant services, is integral to reducing adverse pregnancy-related health outcomes and promoting positive birth experiences. The World Health Organization (WHO) recommends a total of eight ANC visits for pregnant women. However, the ANC coverage rate remains considerably lower among more vulnerable populations, and the quality of care that women receive is inconsistent, often poor, and frequently fails to detect risks in a timely fashion or adequately prepare women for the birth process. While rates of facility-based delivery are on the rise worldwide, disparities persist and the quality of care across facilities remains uneven. Even less information is available on PNC, where services beyond routine immunizations may not be widely available, especially in resource-poor regions. Additionally, limited evidence exists on innovative service delivery approaches and how to effectively scale tested maternal and newborn health (MNH) interventions. This coupled with the fragmented datasets from smaller studies limit our ability to advocate for policy change. The Pregnancy Risk Stratification Innovation and Measurement Alliance (PRiSMA) is implementing a harmonized open cohort study that seeks to evaluate pregnancy risk factors and their associations with adverse pregnancy outcomes, including stillbirth, neonatal mortality and morbidity, and maternal mortality and severe morbidity. The …
This description comes directly from the study's public registry record.
Emily R Smith, ScD, MPH · 12029943589 · emilysmith@gwu.edu
Bethany Freeman, MPH · bethany.freeman@gwu.edu
Always discuss trial participation with your own doctor first.
| Kintampo Health Research Centre | Kintampo, Ghana | Completed |
| Christian Medical College (CMC) Vellore | Vellore, India | Recruiting |
| Kenya Medical Research Institute-Center for Global Health Research | Kisumu, Kenya | Active Not Recruiting |
| Aga Khan University | Karachi, Pakistan | Recruiting |
| University of North Carolina-Global Projects Zambia | Lusaka, Zambia | Completed |
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Source record: clinicaltrials.gov/study/NCT05904145