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Study identifier: NCT05902741 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The Impact of a Race-Based Stress Reduction Intervention

Condition: Racism · Stress · Inflammation  ·  Sponsor: Loyola University

PhaseNA
Planned participants300
Who can joinFemale, 50 Years to 75 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn whether a stress reduction program called Resilience, Stress, and Ethnicity (RiSE) improves well-being, inflammation, and the epigenome in African American (AA) women who have risk factors for heart or metabolic disease. The main question it aims to answer is whether an intervention that integrates cognitive-behavioral strategies focused on the impact that social stress, such as racism, has on the body, racial identity development, and empowerment. Participants will placed in one of the two following groups: * The RiSE program will focus on teaching participants how to reduce their stress levels and will meet online weekly for approximately 2 hours each week for 8 consecutive weeks. * The Health Education program will include education on how to improve general health and will meet online weekly for approximately 2 hours each week for 8 consecutive weeks. Participants will provide saliva to measure cytokines and DNA methylation (DNAm), complete questionnaires, and have blood pressure, heart rate, and weight measured at the following clinic visits: 1. Prior to starting the intervention 2. Mid-way through the intervention (Week 4) 3. End of the intervention (Week 8) 4. Six (6) months after the completion of the intervention

This description comes directly from the study's public registry record.

Talk to the study team

Karen Saban, RN, PhD  ·  773-508-3990  ·  risestudy@luc.edu

Cara Joyce, PhD  ·  464-220-9521  ·  cjoyce6@luc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Loyola University ChicagoMaywood, Illinois, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05902741