Condition: Esophageal Achalasia · Sponsor: Centre Hospitalier Universitaire de Nīmes
Per Oral Endoscopic Myotomy (POEM) is a treatment of choice for achalasia with an excellent safety and efficacy profile. There is a high rate of esophagitis related to gastroesophageal reflux following this procedure. There is no recommendation on the prescription of protein pump inhibitors (PPI) after the procedure and no study has studied the benefit of systematic prescription of PPI after POEM for achalasia. The study authors hypothesize that routine PPI prescribing post-POEM for 12 months would reduce the rate of esophageal acid exposure compared to a symptom-based prescribing strategy.
This description comes directly from the study's public registry record.
Antoine Debourdeau · 06.68.31.94.89 · a-debourdeau@chu-montpellier.fr
Always discuss trial participation with your own doctor first.
| AP-HM | Marseille, France | Recruiting |
| CHU de Montpellier | Montpellier, France | Recruiting |
| Clinique mutualiste Beausoleil | Montpellier, France | Recruiting |
| CHU de Nîmes | Nîmes, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05899842