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Study identifier: NCT05895136 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Novel COMBinATorial Therapy With Albumin and Enoxaparin in Patients With Decompensated Cirrhosis at High-risk of Poor Outcome (COMBAT Trial).

Condition: Liver Cirrhosis · Decompensated Cirrhosis of Liver · Acute on Chronic Liver Failure (ACLF)  ·  Sponsor: European Foundation for Study of Chronic Liver Failure

PhasePhase 2
Planned participants90
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to determine primarily whether a combinatorial therapy based on the administration of human albumin and enoxaparin is safe and effective in patients with decompensated cirrhosis discharged from the hospital. The main questions it aims to answer are: * Is this combinatorial therapy safe and tolerable? * Is this combinatorial therapy effective? * does this combinatorial therapy cost more or less than standard medical therapy? Participants will attend to study visits in which several test will be performed to asses disease evolution while they are taking study medication. Researchers will compare experimental group treated with combinatorial therapy plus standard treatment with control group treated with standard treatment to see if there are differences in the responses to the questions raised above.

This description comes directly from the study's public registry record.

Talk to the study team

Anna Bosch  ·  +34 93 227 14 03  ·  anna.bosch@efclif.com

Always discuss trial participation with your own doctor first.

Locations (9)

Hôpital BeaujonClichy, FranceRecruiting
Universitätsklinikum Aachen AöRAachen, GermanyRecruiting
Universität MünsterMünster, GermanyRecruiting
IRCSS Azienda Ospedaliero Universitaria di Bologna Policlinico di Sant'OrsolaBologna, Emilia-Romagna, ItalyRecruiting
Azienda Ospedaliero-Universitaria "Città della Salute e della Scienza di Torino"Turin, Piedmont, ItalyRecruiting
Hospital Universitari Vall d'Hebron-VHIRBarcelona, Barcelona, SpainRecruiting
Hospital Universitario Ramón y CajalMadrid, Madrid, SpainRecruiting
Hospital Clínic de Barcelona-FCRBBarcelona, SpainRecruiting
Royal Free HospitalLondon, United KingdomNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT05895136