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Study identifier: NCT05888974 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Diagnostic Performance of the Mitral Annulus Velocity Variation Measured by Tissue Doppler to Evaluate the Fluid Responsiveness During the Initial Management of Shock in Patients Admitted to the Emergency Department

Condition: Shock  ·  Sponsor: Centre Hospitalier Universitaire de Nīmes

PhaseN/A
Planned participants187
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Assessing the response to vascular filling in shock is a challenge in emergency medicine. The mitral annulus velocity measured by tissue Doppler (E') has recently been characterized as sensitive to the preload conditions of a patient. The investigators hypothesize that the E' variation (∆E') before and after fluid filling allows us to assess the response to vascular filling. The investigators hypothesize that the ∆E' has a good diagnostic performance to establish whether a patient is responsive to fluid filling, defined by an area under the ROC curve greater than 0.75.

This description comes directly from the study's public registry record.

Talk to the study team

Laura GRAU MERCIER, MD  ·  +33675169725  ·  laura.merciergr@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

CHU de NîmesNîmes, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT05888974