Condition: Nodular Lymphocyte Predominant B-Cell Lymphoma · Recurrent Nodular Lymphocyte Predominant B-Cell Lymphoma · Refractory Nodular Lymphocyte Predominant B-Cell Lymphoma · Sponsor: National Cancer Institute (NCI)
This phase II trial compares mosunetuzumab to the usual treatment (rituximab) for improving survival in patients with nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL). Rituximab and mosunetuzumab are monoclonal antibodies. They bind to a protein called CD20, which is found on B cells (a type of white blood cell) and some types of cancer cells. This may help the immune system kill cancer cells. Mosunetuzumab may be more effective at extending survival in patients with NLPHL than the usual approach with rituximab.
This description comes directly from the study's public registry record.
Contact details are listed per location below or on the registry record.
Always discuss trial participation with your own doctor first.
| City of Hope Comprehensive Cancer Center | Duarte, California, United States | Recruiting |
| UM Sylvester Comprehensive Cancer Center at Aventura | Aventura, Florida, United States | Recruiting |
| UM Sylvester Comprehensive Cancer Center at Coral Gables | Coral Gables, Florida, United States | Recruiting |
| UM Sylvester Comprehensive Cancer Center at Coral Springs | Coral Springs, Florida, United States | Recruiting |
| UM Sylvester Comprehensive Cancer Center at Deerfield Beach | Deerfield Beach, Florida, United States | Recruiting |
| UM Sylvester Comprehensive Cancer Center at Doral | Doral, Florida, United States | Recruiting |
| UM Sylvester Comprehensive Cancer Center at Hollywood | Hollywood, Florida, United States | Recruiting |
| University of Miami Miller School of Medicine-Sylvester Cancer Center | Miami, Florida, United States | Recruiting |
| UM Sylvester Comprehensive Cancer Center at Kendall | Miami, Florida, United States | Recruiting |
| University of Miami Sylvester Comprehensive Cancer Center at Sole Mia | North Miami, Florida, United States | Recruiting |
| UM Sylvester Comprehensive Cancer Center at Plantation | Plantation, Florida, United States | Recruiting |
| Emory University Hospital/Winship Cancer Institute | Atlanta, Georgia, United States | Active Not Recruiting |
+ 25 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT05886036