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Study identifier: NCT05885529 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Glial Fibrillary Acidic Protein (GFAP) and Ubiquitin Carboxy-terminal Hydrolase L1 (UCH-L1) to Exclude Lesions Linked to Significant Traumatic Brain Injuries

Condition: Traumatic Brain Injury  ·  Sponsor: Centre Hospitalier Princesse Grace

PhaseN/A
Planned participants1500
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this observational study is to evaluate the performance of UCH-L1 and GFAP combined in patients with a mild traumatic brain injury. The main question : • Does the combination of UCH-L1 and GFAP can exclude brain injuries detected with CT scan in the first twelve hours after a mild traumatic brain injury? Participants will do the exams planed in routine care and : * during the expected blood sampling an additional blood sample will be done, * seven days after the discharge a call will be done by the investigator.

This description comes directly from the study's public registry record.

Talk to the study team

Yann-Erick CLAESSENS, MD-PhD  ·  97 98 99 00  ·  yann-erick.claessens@chpg.mc

Nicolas RIJO, CRA  ·  97 98 99 00  ·  recherche.clinique@chpg.mc

Always discuss trial participation with your own doctor first.

Locations (15)

Centre Hospitalier Universitaire d'AngersAngers, FranceRecruiting
Hôpital Gabriel-Montpied - CHU de Clermont-FerrandClermont-Ferrand, FranceRecruiting
Hôpital François Mitterrand - CHU de DijonDijon, FranceRecruiting
Hôpital Nord - CHU de Grenoble-AlpesGrenoble, FranceRecruiting
Hospices Civils de LyonLyon, FranceRecruiting
Hôpital Lapeyronie - CHU de MontpellierMontpellier, FranceNot Yet Recruiting
Hôtel Dieu - CHU de NantesNantes, FranceRecruiting
Hôpital Pasteur CHU de NiceNice, FranceRecruiting
Hôpital Carémeau - CHU de NîmesNîmes, FranceRecruiting
AP-HP Nord LariboisièreParis, FranceRecruiting
AP-HP Sorbonne Université, site Pitié-SalpêtrièreParis, FranceRecruiting
Hôpital Saint-JosephParis, FranceRecruiting

+ 3 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05885529