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Study identifier: NCT05883358 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Kratom Use Disorder Management Using Clonidine and/or Buprenorphine

Condition: Withdrawal Syndrome  ·  Sponsor: Salem Anaesthesia Pain Clinic

PhaseN/A
Planned participants50
Who can joinAll sexes, 20 Years to 99 Years
Healthy volunteersYes

About this study

Kratom is used for stimulant, analgesic, anxiolytic, and sedative effects. There is inadequate knowledge about Kratom addiction. Kratom withdrawal may be treated like opioid withdrawal. Prospective observational crossover study of consenting adults who are undergoing Kratom withdrawal management. On alternate weeks, each patient receives treatment using Buprenorphine 5cmg/hr patch; or Clonidine tablet 0.1mg 4hourly; or combined Clonidine tablet 0.1mg 4hourly + Buprenorphine 5cmg/hr patch. Each patient will undergo treatment for 12 weeks. Patients will use Subjective Opiate Withdrawal Scale (SOWS) to collect data on daily basis. SOWS is a patient-administered tool that is used to record the severity and presence of opiate withdrawal. The physician will also use Clinical Opiate Withdrawal Scale (COWS) to collect data on weekly basis. COWS is a clinician-administered tool that is used to record the signs of opiate withdrawal. A change in the COWS and SOWS scores by 6-points is considered significant.

This description comes directly from the study's public registry record.

Talk to the study team

Olu Bamgbade, MD,FRCPC  ·  17786286600  ·  salem.painclinic@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Salem Anaesthesia Pain ClinicSurrey, British Columbia, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT05883358