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Study identifier: NCT05881239 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Digital Accessible Remote Olfactory Mediated Health Assessments for Preclinical AD

Condition: Subjective Cognitive Concerns · Mild Cognitive Impairment · Mild Behavioral Impairment  ·  Sponsor: Massachusetts General Hospital

PhaseN/A
Planned participants250
Who can joinAll sexes, 18 Years to 100 Years
Healthy volunteersYes

About this study

The goal of this study is to objectively test one's sense of smell, called olfaction, in participants with Subjective Cognitive Concerns (SCC), Mild Cognitive Impairment, Mild Behavioral Impairment (MBI), and age-matched controls. The main question it aims to answer is whether the AROMHA Brain Health Test could serve as a predictive biomarker of neurodegenerative disorders. This understanding will aid in the development of a noninvasive, cost-effective diagnostic tool that reliably and specifically distinguishes disease and normal aging populations. Participants will take the approximately 45-minute AROMHA Brain Health Smell Test where they will peel and sniff labels on the physical smell cards and answer questions on the web-based app relating to what they smelled. Participants will undergo tests for odor intensity, odor identification, odor discrimination, and episodic olfactory memory, but will not be provided the results of these tests.

This description comes directly from the study's public registry record.

Talk to the study team

Mark W Albers, MD PhD  ·  617-724-7401  ·  albers.mark@mgh.harvard.edu

Alefiya Albers, PhD  ·  AALBERS@mgh.harvard.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05881239