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Study identifier: NCT05879965 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Prospective Study for the FOLLOW-UP of Human Monkeypox Cases and Smallpox Vaccinees at Risk

Condition: Monkeypox  ·  Sponsor: Institute of Tropical Medicine, Belgium

PhaseN/A
Planned participants345
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this observational study is to describe possible physical and psychological sequelae after an mpox infection and to evaluate the longevity of B- and T-cell immune responses in former mpox patients and vaccine recipients. The main questions it aims to answer are: * Are there any physical or pschological sequelae after mpox infection? * Is the humoral and/or cellular immune response to MPOX (or vaccinia) virus) durable? * Do the patients develop strong local immunity in comparison to systemic immunity? * How long is the virus still detectable in semen, saliva or the ano-rectal region? Participants will answer a questionnaire, samples with blood, saliva and semen as well as anal swabs will be collected. Follow-up visits 8, 16 and 24, 36, 48, and 60 months after infection or vaccination are planned. A healthy control group will be recruited in our HIV-PrEP clinic.

This description comes directly from the study's public registry record.

Talk to the study team

Study Coordinator  ·  +32(0)33455672  ·  bsmekens@itg.be

Always discuss trial participation with your own doctor first.

Locations (1)

Institute of Tropical MedicineAntwerp, BelgiumRecruiting

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Source record: clinicaltrials.gov/study/NCT05879965