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Study identifier: NCT05879432 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

LSALT Peptide for Prevention or Attenuation of Acute Kidney Injury (AKI) in Patients Undergoing On-Pump Cardiac Surgery

Condition: Acute Kidney Injury · Cardiac Surgery  ·  Sponsor: Arch Biopartners Inc.

PhasePhase 2
Planned participants240
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

To evaluate the percentage of subjects with AKI within 7 days following on-pump cardiac surgery defined by the KDIGO (Kidney Disease: Improving Global Outcomes) criteria: 1. Increase in baseline (pre-surgery) serum creatinine (SCr) by ≥26.5 μmol/L (≥0.3 mg/dL) within 7 days; OR 2. Increase in baseline SCr to ≥1.5 times baseline, which is known or presumed to have occurred within the first 7 days following surgery; OR 3. Urine output \< 0.5 mL/kg/h for \>6 hours.

This description comes directly from the study's public registry record.

Talk to the study team

Richard Muruve  ·  +1 647 428 7031  ·  rm@archbiopartners.com

David Luke  ·  dl@archbiopartners.com

Always discuss trial participation with your own doctor first.

Locations (9)

Cumming School of Medicine & Libin Cardiovascular Centre, University of CalgaryCalgary, Alberta, CanadaRecruiting
Royal Columbian HospitalNew Westminster, British Columbia, CanadaRecruiting
Unity Health Toronto, St. Michael's HospitalToronto, Ontario, CanadaRecruiting
University Health Network, Toronto General HospitalToronto, Ontario, CanadaRecruiting
Gazi UniversityYenimahalle, Ankara, Turkey (Türkiye)Completed
Kosuyolu High Specialization Training and Research HospitalKartal, Istanbul, Turkey (Türkiye)Completed
Erciyes University, Faculty of Medicine - Semiha Kibar Organ Transplant & Dialysis HospitalMelikgazi, Kayseri, Turkey (Türkiye)Completed
Kocaeli University, Faculty of Medicine Practices and Research Hospitalİzmit, Kocaeli, Turkey (Türkiye)Completed
Sütçü İmam University, Faculty of MedicineKahramanmaraş, Onikişubat, Turkey (Türkiye)Completed

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Source record: clinicaltrials.gov/study/NCT05879432