Condition: Glioblastoma, IDH-Wildtype · MGMT-Unmethylated Glioblastoma · Sponsor: Northwestern University
This phase II trial tests how well the combination of WP1066 and radiation therapy works in treating newly diagnosed glioblastoma. Glioblastoma is difficult to treat effectively because the cells within the tumor vary widely and are controlled by factors within and around the tumor, requiring multiple approaches to treat the tumor. The study drug WP1066 targets a specific pathway, known as STAT3, which is responsible for promoting tumor growth and causing the body's immune system to avoid attacking the tumor. Radiation therapy prevents glioblastoma from growing. Giving WP1066 with radiation therapy may prevent glioblastoma from growing and prolong survival.
This description comes directly from the study's public registry record.
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| Northwestern University | Chicago, Illinois, United States | Recruiting |
| Northwestern Medicine: Warrenville | Warrenville, Illinois, United States | Active Not Recruiting |
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Source record: clinicaltrials.gov/study/NCT05879250