● Recruiting

iMmune SignAtures and Clinical outComes in AP

Condition: Acute Pancreatitis · Sponsor: Ohio State University

PhaseN/A

Planned participants198

Who can joinAll sexes, 18 Years to 75 Years

Healthy volunteersNo

About this study

The MoSAIC study is a prospective, observational study designed to develop an early prediction tool for severe acute pancreatitis (SAP) and define a distinct immunologic profile compared to moderate acute pancreatitis (MAP). The aims are to validate a new multi-cytokine panel for early prediction of SAP and to identify the specific immune cells that correspond with cytokine signatures in early acute pancreatitis to characterize the immune pathways driving the development of SAP. Participants will provide blood samples and complete patient surveys and interviews within 36 hours of hospital presentation, at 48 hours, and hospital day 7 (if admitted). Data on hospital stay, medical history, clinical course, and severity of disease will be collected.

This description comes directly from the study's public registry record.

Talk to the study team

Zoe Krebs, BA · 614-685-3619 · zoe.krebs@osumc.edu

Samantha Terhorst, MS · 614-685-3618 · samantha.terhorst@osumc.edu

Always discuss trial participation with your own doctor first.

Locations (5)

University of Southern California	Los Angeles, California, United States	Not Yet Recruiting
University of Illinois Chicago	Chicago, Illinois, United States	Not Yet Recruiting
The Ohio State University	Columbus, Ohio, United States	Recruiting
University of Pittsburgh	Pittsburgh, Pennsylvania, United States	Not Yet Recruiting
Benaroya Research Institute	Seattle, Washington, United States	Not Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT05878236