← Eichor
Study identifier: NCT05876754 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

An Early Access Study of Ivosidenib in Patients With a Pretreated Locally Advanced or Metastatic Cholangiocarcinoma

Condition: Cholangiocarcinoma  ·  Sponsor: Servier Affaires Médicales

PhasePhase 3
Planned participants220
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

A Phase 3b research study to consolidate the data that ivosidenib is safe and effective in adult patients with previously treated, locally advanced, or metastatic cholangiocarcinoma (CCA). All patients who meet inclusion criteria will be enrolled to receive ivosidenib tablets orally once daily for 28 day cycles, continuing as long as clinical benefit and consent for participation is maintained. There will be a minimum of 6 study visits from screening until the final follow-up, if one cycle of treatment is completed and consent is maintained through 18 months of follow-up. Each additional cycle completed will add one study visit, on the first day of each cycle.

This description comes directly from the study's public registry record.

Talk to the study team

Institut de Recherches Internationales Servier, Clinical Studies Department  ·  +33 1 55 72 60 00  ·  scientificinformation@servier.com

Always discuss trial participation with your own doctor first.

Locations (84)

Erebouni MCYerevan, ArmeniaCompleted
National Center of Oncology of Ra MYerevan, ArmeniaCompleted
Royal brisbane & Women's HospitalBrisbane, AustraliaCompleted
St Vincent's HospitalFitzroy, AustraliaCompleted
St John of God Hospital - Bendat Family Comprehensive Cancer Centre (BFCCC)Subiaco, AustraliaCompleted
Kinghorn Cancer CentreSydney, AustraliaCompleted
The Queen Elizabeth HospitalWoodville, AustraliaCompleted
Medizinische Universitaet GrazGraz, AustriaCompleted
Ordensklinikum Linz GmbHLinz, AustriaCompleted
Universitaetsklinik fuer Innere Medizin III, mit Hämatologie, internistischer Onkologie, Hämostaseologie, Infektiologie, Rheumatologie und Onkologisches ZentrumSalzburg, AustriaCompleted
Medizinische Universitaet Wien Universitaetsklinik fuer Innere Medizin IVienna, AustriaCompleted
Universite Libre de Bruxelles ULB -Brussels, BelgiumCompleted

+ 72 more locations — full list on the registry record.

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT05876754