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Study identifier: NCT05876312 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Safety, Tolerability, PK and PD of ADX-038 in Healthy Participants and Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients

Condition: Paroxysmal Nocturnal Hemoglobinuria (PNH)  ·  Sponsor: ADARx Pharmaceuticals, Inc.

PhasePhase 1/Phase 2
Planned participants50
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

The first-in-human Phase 1/Phase 2a study described herein will evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of ADX-038 in both healthy participants (HP) and in patients with paroxysmal nocturnal hemoglobinuria (PNH).

This description comes directly from the study's public registry record.

Talk to the study team

Stephanie Leyva  ·  877-232-7974  ·  info@adarx.com

Always discuss trial participation with your own doctor first.

Locations (4)

Nucleus Network BrisbaneBrisbane, Queensland, AustraliaCompleted
Peter MacCallum Cancer CentreMelbourne, Victoria, AustraliaCompleted
Royal Melbourne HospitalParkville, Victoria, AustraliaRecruiting
Richmond Pharmacology LtdLondon, London, United KingdomCompleted

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Source record: clinicaltrials.gov/study/NCT05876312