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Study identifier: NCT05870423 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Improving Peptide Receptor Radionuclide Therapy With PARP Inhibitors

Condition: Neuroendocrine Tumors · Peptide Receptor Radionuclide Therapy  ·  Sponsor: Erasmus Medical Center

PhasePhase 1
Planned participants24
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a phase 1 dose-escalation study to determine the maximum tolerated dose of the PARP inhibitor olaparib in combination with PRRT in patients with a well-differentiated advanced gastroenteropancreatic NET (GEP NET), progressive after PRRT. As secondary objectives, efficacy, pharmacokinetics and biomarker response will be investigated.

This description comes directly from the study's public registry record.

Talk to the study team

M.N. Becx  ·  43449  ·  m.becx@erasmusmc.nl

Always discuss trial participation with your own doctor first.

Locations (1)

Erasmus MCRotterdam, South Holland, NetherlandsRecruiting

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Source record: clinicaltrials.gov/study/NCT05870423