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Study identifier: NCT05869279 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Allogeneic CARCIK-CD19 in Adults/Pediatric B-cell NHL or Chronic Lymphocytic Leukemia

Condition: B-cell NHL · CLL  ·  Sponsor: Fondazione Matilde Tettamanti Menotti De Marchi Onlus

PhasePhase 1/Phase 2
Planned participants29
Who can joinAll sexes, 1 Year to no upper limit
Healthy volunteersNo

About this study

This is a single arm, open-label, multi-center, phase I/II study to determine the engraftment, safety and clinical activity of allogeneic CARCIK-CD19 cells in adult and pediatric patients with relapsed/refractory mature B-cell neoplasia expected to express CD19 i.e. B-cell NHL and CLL. CARCIK-CD19 will be produced from the peripheral blood of an at least haploidentical familial donor.

This description comes directly from the study's public registry record.

Talk to the study team

Andrea Biondi, MD  ·  +39039233  ·  segreteriadirezionecp@fondazionembbm.it

Alessandro Rambaldi, MD  ·  +39035267  ·  ematologiasegr@asst-pg23.it

Always discuss trial participation with your own doctor first.

Locations (1)

Ospedale Papa Giovanni XXIIIBergamo, BG, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT05869279