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Study identifier: NCT05868837 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Rituximab EfFicacy IN MyasthEnia Gravis (REFINE)

Condition: Myasthenia Gravis, Generalized  ·  Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS

PhasePhase 3
Planned participants40
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The primary objective of this phase III trial is to investigate if Rituximab can reduce patients' functional impairment caused by MG. The secondary objectives of this trial are to assess whether treatment with rituximab in patients with MG will: * Allow faster and greater corticosteroid tapering * Reduce the frequency of exacerbations * Improve quality of life * Offer an acceptable safety and tolerability profile.

This description comes directly from the study's public registry record.

Talk to the study team

Raffaele Iorio  ·  +393347185128  ·  raffaele.iorio@policlinicogemelli.it

Always discuss trial participation with your own doctor first.

Locations (1)

Policlinico A. Gemelli IRCCSRoma, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT05868837