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Study identifier: NCT05868174 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Combination of 177Lu-TLX250 and Peposertib in Patients With Carbonic Anhydrase IX -Expressing Solid Tumors

Condition: Solid Tumor, Adult · Advanced Solid Tumor · Advanced Renal Cell Carcinoma  ·  Sponsor: Telix Pharmaceuticals (Innovations) Pty Limited

PhasePhase 1
Planned participants36
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is an open label, single-arm, multicentre dose escalation (Part 1) and dose expansion (Part 2) study to evaluate different combinations of 3 radioactive dose levels of 177Lu-TLX250 administered intravenously with 3 different doses of peposertib in patients with CAIX-expressing solid tumors.

This description comes directly from the study's public registry record.

Talk to the study team

MEDICAL DIRECTOR, MD

Always discuss trial participation with your own doctor first.

Locations (5)

Macquarie UniversityNorth Ryde, New South Wales, AustraliaRecruiting
Ashford (Icon) Cancer CentreAdelaide, AustraliaRecruiting
Princess Alexandra HospitalBrisbane, AustraliaRecruiting
Austin HealthMelbourne, AustraliaRecruiting
GenesisCare MurdochPerth, AustraliaRecruiting

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Source record: clinicaltrials.gov/study/NCT05868174