← Eichor
Study identifier: NCT05867472 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Advancing Brain Outcomes in Pediatric Critically Ill Patients Sedated With Volatile AnEsthestic Agents

Condition: Intensive Care Units, Pediatric · Anesthetics, Inhalation · Mechanically Ventilated, Critically Ill Children  ·  Sponsor: Sunnybrook Health Sciences Centre

PhasePhase 3
Planned participants60
Who can joinAll sexes, 1 Month to 18 Years
Healthy volunteersNo

About this study

The goal of a pilot study is to test a study plan to see if it is appropriate for a larger study. This study plan is looking at whether the use of inhaled sedatives (medications that help people be calm and sleep) can reduce delirium (extreme confusion) in children who need a ventilator (breathing machine) compared to IV or oral sedatives. The main question\[s\] it aims to answer are: * Will people join the study? (recruitment) * Will participants finish the study? * Will healthcare teams accept the study procedures? Participants will be randomized to receive study treatment (inhaled sedation) or standard of care (IV sedation). They will be monitored daily for up to 28 days. They will complete memory, thinking and behaviour tasks after 9-12 months.

This description comes directly from the study's public registry record.

Talk to the study team

Sunnybrook Research Institute, Program Manager - Centre for Clinical Trials Services  ·  416-480-6100  ·  ABOVETrial@sunnybrook.ca

Always discuss trial participation with your own doctor first.

Locations (3)

McMaster Children's HospitalHamilton, Ontario, CanadaRecruiting
Children's Hospital - London Health Sciences CentreLondon, Ontario, CanadaRecruiting
The Hospital for Sick Children (SickKids)Toronto, Ontario, CanadaRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT05867472