Condition: Large Hiatal Hernia · Sponsor: University Hospital, Bordeaux
The large hiatal hernia (LHH) now represents approximately 50% of laparoscopic antireflux surgical practice. In a non-comparative retrospective study of 399 patients operated for LHH with onlay patch of a bioprosthetic absorbable (Gore® Bio-A® HH0710) mesh with a mean follow-up of 44 months, 16% had a symptomatic recurrence with 7,9% requiring reoperation, one patient had oesophageal stenosis. No comparative effectiveness data exist to date. Hypothesis: the incidence of postoperative hiatus hernia would be reduced by the addition of biosynthetic absorbable mesh reinforcement to a standardized suture repair technique, as compared to laparoscopic repair without mesh, without increasing the risk of complications. The main objective is to compare the radiologic recurrence rate at 2 years between standardized herniorrhaphy with onlay biosynthetic absorbable mesh repair versus standardized herniorrhaphy with no mesh in symptomatic LHH.
This description comes directly from the study's public registry record.
Caroline Gronnier, MD, PhD · + 33 5 57 65 60 05 · caroline.gronnier@chu-bordeaux.fr
Valérie Aurillac-Lavignolle · +33 5 57 82 24 77 · valerie.aurillac@chu-bordeaux.fr
Always discuss trial participation with your own doctor first.
| CH de la Côte Basque | Bayonne, France | Not Yet Recruiting |
| Hôpital Jean Minjoz, CHRU de Besançon | Besançon, France | Not Yet Recruiting |
| Hôpital Cavale blanche, CHRU de Brest | Brest, France | Not Yet Recruiting |
| Hôpital Côte de nacre, CHU Caen Normandie | Caen, France | Not Yet Recruiting |
| Hôpital Estang | Clermont-Ferrand, France | Not Yet Recruiting |
| Hôpital Louis-Mourier, AP-HP | Colombes, France | Not Yet Recruiting |
| Hôpital Nord, CHU de Grenoble | La Tronche, France | Not Yet Recruiting |
| Hôpital Claude Huriez, CHRU de Lille | Lille, France | Not Yet Recruiting |
| Polyclinique du bois, Hôpital privé Le Bois | Lille, France | Not Yet Recruiting |
| Hôpital Dupuytren 1, CHU de Limoges | Limoges, France | Not Yet Recruiting |
| Hôpital de la Croix-Rousse, HCL | Lyon, France | Not Yet Recruiting |
| Hôpital Saint Eloi, CHU de Montpellier | Montpellier, France | Not Yet Recruiting |
+ 14 more locations — full list on the registry record.
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT05867225