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Study identifier: NCT05866562 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Dupilumab in the Treatment of Pediatric Alopecia Areata

Condition: Alopecia Areata  ·  Sponsor: Icahn School of Medicine at Mount Sinai

PhasePhase 2
Planned participants76
Who can joinAll sexes, 6 Years to 17 Years
Healthy volunteersNo

About this study

This is a prospective, randomized, double-blind, placebo-controlled clinical trial. The study will take place at four sites. This trial will enroll a total of 76 children and adolescents with moderate to severe AA (affecting at least 30% of the scalp) at the time of screening with a targeted 61 participants completing through Week 48. All subjects must have evidence of hair regrowth within the last 7 years of their last episode of hair loss; and have screening IgE ≥200 and/or have personal and/or familial history of atopy. Study participation will be up to 124 weeks, consisting of: a screening period of up to 4 weeks; a 48-week placebo-controlled period; a 48-week open-label extension period; followed by a 24-week follow-up period.

This description comes directly from the study's public registry record.

Talk to the study team

Benjamin Ungar, MD  ·  212-241-3288  ·  benjamin.ungar@mountsinai.org

Always discuss trial participation with your own doctor first.

Locations (5)

University of California, IrvineIrvine, California, United StatesRecruiting
University of California San DiegoSan Diego, California, United StatesRecruiting
Ann & Robert H. Lurie Children's Hospital of ChicagoChicago, Illinois, United StatesRecruiting
Northwestern University Feinberg School of MedicineChicago, Illinois, United StatesRecruiting
Icahn School of Medicine at Mount SinaiNew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05866562