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Study identifier: NCT05859750 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of AK104 With Chemotherapy as First-line Treatment in Patients With Advanced Pancreatic Cancer

Condition: Pancreatic Cancer  ·  Sponsor: Akeso

PhasePhase 2
Planned participants78
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This study is a multicenter, open-label, phase II study to evaluate the safety, tolerability, pharmacokinetics (PK), immunogenicity, pharmacodynamics (PD) and anti-tumor activities of AK104,a PD-1/CTLA-4 bispecific antibody, in combination with chemotherapy as first-line therapy in subjects with advanced unresectable or metastatic pancreatic ductal adenocarcinoma.

This description comes directly from the study's public registry record.

Talk to the study team

Zhifang Yao, MD  ·  +86-0760-89873999  ·  clinicaltrials@akesobio.com

Always discuss trial participation with your own doctor first.

Locations (7)

Peking Union Medical College HospitalBeijing, Beijing Municipality, ChinaRecruiting
Sun Yat-sen University Cancer CenterGuangzhou, Guangdong, ChinaRecruiting
Union Hospital Tongji Medical College Huazhong University of Science And TechnologyWuhan, Hubei, ChinaRecruiting
Shandong Cancer HospitalJinan, Shandong, ChinaRecruiting
Shanghai Changhai HospitalShanghai, Shanghai Municipality, ChinaRecruiting
Zhejiang Cancer HospitalHangzhou, Zhejiang, ChinaRecruiting
Zhejiang Provincial People's hospitalHangzhou, Zhejiang, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05859750