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Study identifier: NCT05857969 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling

Condition: Recurrent Childhood Acute Myeloid Leukemia · Recurrent Childhood Acute Lymphoblastic Leukemia · Recurrent Childhood Large Cell Lymphoma  ·  Sponsor: Florida International University

PhasePhase 1
Planned participants65
Who can joinAll sexes, 1 Day to 21 Years
Healthy volunteersNo

About this study

Functional precision medicine (FPM) is a relatively new approach to cancer therapy based on direct exposure of patient- isolated tumor cells to clinically approved drugs and integrates ex vivo drug sensitivity testing (DST) and genomic profiling to determine the optimal individualized therapy for cancer patients. In this study, we will enroll relapsed or refractory pediatric cancer patients with tissue available for DST and genomic profiling from the South Florida area, which is 69% Hispanic and 18% Black. Tumor cells collected from tissue taken during routine biopsy or surgery will be tested.

This description comes directly from the study's public registry record.

Talk to the study team

Diana Azzam, PhD  ·  305-348-9043  ·  fpmlab@fiu.edu

Lillian Garvin  ·  800-533-1792  ·  exvivotrial@nicklaushealth.org

Always discuss trial participation with your own doctor first.

Locations (1)

Nicklaus Children's HospitalMiami, Florida, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05857969