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Study identifier: NCT05856981 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors

Condition: Solid Tumor, Adult · Metastatic Solid Tumor · Refractory Cancer  ·  Sponsor: Sairopa B.V.

PhasePhase 1
Planned participants130
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This first-in-human, open-label, multicenter, multi-arm dose-escalation study is designed to evaluate the safety, PK, and PD of ADU-1805, an anti- SIRPα monoclonal antibody, as monotherapy and in combination with pembrolizumab (anti-PD-1 antibody).

This description comes directly from the study's public registry record.

Talk to the study team

Sairopa Clinical Team  ·  0031 85 90 26 939  ·  clinical@sairopa.com

Always discuss trial participation with your own doctor first.

Locations (7)

Henry Ford Cancer InstituteDetroit, Michigan, United StatesRecruiting
Washington University Medical CampusSt Louis, Missouri, United StatesRecruiting
Gabrail Cancer & Research CenterCanton, Ohio, United StatesRecruiting
Virginia Cancer SpecialistsFairfax, Virginia, United StatesRecruiting
Grand Hopital de Charleroi (GHdC) - Hopital Notre DameCharleroi, BelgiumRecruiting
Hosp 12 de OctubreMadrid, SpainRecruiting
Hospital General Universitario Gergorio MaranonMadrid, SpainRecruiting

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Source record: clinicaltrials.gov/study/NCT05856981