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Study identifier: NCT05856890 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

HepB mAb19 in Individuals With Chronic Hepatitis B Infection

Condition: Hepatitis b Virus · Hepatitis B  ·  Sponsor: Rockefeller University

PhasePhase 1
Planned participants37
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

This is a first-in-human, placebo-controlled, single dose, dose-escalation phase 1 study to evaluate the safety, pharmacokinetics and antiviral activity of a highly potent neutralizing anti-HBV monoclonal antibody (mAb), HepB mAb19, which targets the S-protein in individuals with chronic hepatitis B (CHB) on nucleos(t)ide analog therapy (NRTI).

This description comes directly from the study's public registry record.

Talk to the study team

Recruitment Specialist  ·  800-782-2737  ·  rucares@rockefeller.edu

Marina Caskey, MD  ·  212-327-7396  ·  mcaskey@rockefeller.edu

Always discuss trial participation with your own doctor first.

Locations (2)

NYU Langone HealthNew York, New York, United StatesRecruiting
The Rockefeller UniversityNew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05856890