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Study identifier: NCT05856851 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Intra-arterial Alteplase for Acute Ischemic Stroke After Mechanical Thrombectomy

Condition: Stroke, Acute Ischemic  ·  Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

PhasePhase 3
Planned participants324
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

A multicenter, prospective, open-label, blinded endpoint, randomized controlled trial aiming at evaluating the efficacy and safety of intra-arterial recombinant human tissue plasminogen activator (rt-PA) after successful recanalization of acute large vessel occlusion in the anterior circulation by mechanical thrombectomy in improving the 90-day functional outcome.

This description comes directly from the study's public registry record.

Talk to the study team

Xinguang Yang  ·  86-20-81332619  ·  yangxinguang0926@163.com

Xiongjun He  ·  075523360593  ·  drxjhe@163.com

Always discuss trial participation with your own doctor first.

Locations (2)

Sun Yat-Sen Memorial Hospital, Sun Yat-Sen UniversityGuangzhou, Guangdong, ChinaRecruiting
Shenzhen Hospital of Southern Medical UniversityShenzhen, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05856851