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Study identifier: NCT05855811 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

PREventing Second Cancers With DOSTARlimab

Condition: Recurrent Cancer · Primary Cancer · Second Cancer  ·  Sponsor: Centre Leon Berard

PhasePhase 2
Planned participants400
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

PredoSTAR is a multicenter, randomized, open-label phase II study proposed to patients at high risk of SPC and in whom the treatment of the FPC does not include immunotherapy. Dostarlimab treatment will be started within 6 months after the completion of treatment for localized FPC (i.e. after the end of last CT, RT cure or surgery with a wash-out period of 4 weeks before to start Dostarlimab). Eligible patients will be randomized (1:1) to receive: * Arm Dostarlimab : 4 intravenous (IV) injections of dostarlimab, Q3W or * Arm No treatment

This description comes directly from the study's public registry record.

Talk to the study team

Jean-Yves BLAY, MD, PhD  ·  4 78 78 51 26  ·  jean-yves.blay@lyon.unicancer.fr

Always discuss trial participation with your own doctor first.

Locations (5)

Centre François BaclesseCaen, FranceRecruiting
Centre Jean PerrinClermont-Ferrand, FranceRecruiting
Centre Léon BérardLyon, FranceRecruiting
Institut Claudius RegaudToulouse, FranceRecruiting
Institut Gustave RoussyVillejuif, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT05855811