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Study identifier: NCT05855369 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study of Chemosensory Enhancement Through Neuromodulation Training (SCENT for Long COVID)

Condition: Smell Dysfunction · Olfactory Disorder · Long COVID  ·  Sponsor: Medical University of South Carolina

PhasePhase 2/Phase 3
Planned participants145
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

Persistent smell loss that can include diminished or distorted smell function is a common symptom of long COVID syndrome. There are limited treatment options for long COVID-related smell loss. This study aims to determine the efficacy of two at-home treatments, smell training and non-invasive trigeminal nerve stimulation. This study requires participants to conduct daily at-home treatment sessions, attend three in-person study visits at the MUSC Department of Psychiatry and Behavioral Sciences, and complete electronic questionnaires over the 12-week trial, and again at the six-month timepoint. Participants in this trial may benefit directly with an improvement in sense of smell. However, participation may also help society more generally, as this study will provide new information about long COVID-related smell loss and its treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Bernadette M. Cortese, Ph.D.  ·  843-792-6922  ·  corteseb@musc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Medical University of South CarolinaCharleston, South Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05855369