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Study identifier: NCT05852990 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Glutamine Plus L. Reuteri Prevents TKI Therapy-diarrhea in Patients With NSCLC

Condition: Non-Small Cell Lung Cancer With EGFR Mutation  ·  Sponsor: Instituto Nacional de Cancerologia de Mexico

PhasePhase 3
Planned participants28
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

This open-label randomized clinical trial aims to evaluate the glutamine plus Lactobacillus reuteri supplementation effect in a standard-of-care diet in EGFR mutant patients with advanced non-small cell lung cancer (NSCLC) under tyrosine kinase inhibitors (TKIs) therapy. The main question it aims to answer is ¿What is the effect of glutamine plus L. reuteri added to an astringent diet in preventing diarrhea generated by TKI therapy? Patients will receive an astringent diet supplemented with 10 grams of glutamine and L. reuteri (100 million CFU). Researchers will compare the Glutamine plus L. reuteri diet with a standard astringent diet to see if TKI therapy diarrhea is prevented.

This description comes directly from the study's public registry record.

Talk to the study team

Oscar G Arrieta Rodriguez, M.D., M.Sc.  ·  556280400  ·  ogar@unam.mx

Always discuss trial participation with your own doctor first.

Locations (1)

Instituto Nacional de Cancerologia de MexicoMexico City, Mexico City, MexicoRecruiting

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Source record: clinicaltrials.gov/study/NCT05852990