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Study identifier: NCT05851508 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

The Effecttiveness of Intratympanic Methylprednisolon Injections Compared to Placebo in the Treatment of Vertigo Attacks in Meniere's Disease

Condition: Meniere Disease  ·  Sponsor: Leiden University Medical Center

PhasePhase 3
Planned participants148
Who can joinAll sexes, 18 Years to 100 Years
Healthy volunteersYes

About this study

Ménière's disease is an inner ear disorder in which patients suffer from attacks of vertigo, tinnitus and hearing loss. To date, it is unclear what the best treatment for this condition is. Giving injections in the inner ear with the adrenal cortical hormone methylprednisolone is a treatment that is already widely used, but still there is insufficient evidence in the effectiveness of this treatment. This multicenter trial compares a patient group which receives injections of methylprednisolone to a patient group which receives placebo injections. Subsequently, dizziness, tinnitus, hearing loss and quality of life will be assed and compared for the above mentioned groups, over a period of one year.

This description comes directly from the study's public registry record.

Talk to the study team

Maud Boreel, MD  ·  +3171 526 9111  ·  m.m.e.boreel@lumc.nl

Babette van Esch, MD, PHD  ·  +3171 526 9111  ·  b.f.van_esch@lumc.nl

Always discuss trial participation with your own doctor first.

Locations (1)

Leiden University Medical CentreLeiden, South Holland, NetherlandsRecruiting

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Source record: clinicaltrials.gov/study/NCT05851508