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Study identifier: NCT05848687 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II

Condition: Lymphoblastic Leukemia  ·  Sponsor: Tanja Andrea Gruber

PhasePhase 1/Phase 2
Planned participants90
Who can joinAll sexes, N/A to 1 Year
Healthy volunteersNo

About this study

The purpose of this study is to improve upon the TINI study treatment. The study will test the ability of a type of immunotherapy called blinatumomab to clear persistent leukemia. Blinatumomab targets CD19 which is located on the leukemia cells outer membrane.

This description comes directly from the study's public registry record.

Talk to the study team

Tanja A Gruber, MD, PhD  ·  650 723 5535  ·  tagruber@stanford.edu

Always discuss trial participation with your own doctor first.

Locations (24)

Phoenix Children's HospitalPhoenix, Arizona, United StatesRecruiting
Arkansas Children's HospitalLittle Rock, Arkansas, United StatesRecruiting
Children's Hospital Los AngelesLos Angeles, California, United StatesRecruiting
Valley Children's HospitalMadera, California, United StatesRecruiting
Children's Hospital of Orange CountyOrange, California, United StatesRecruiting
Stanford UniversityPalo Alto, California, United StatesRecruiting
Rady Children's Hospital San DiegoSan Diego, California, United StatesNot Yet Recruiting
Arnold Palmer Hospital for ChildrenOrlando, Florida, United StatesRecruiting
Children's Hospital of MinnesotaMinneapolis, Minnesota, United StatesRecruiting
Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesRecruiting
Novant Health - Hemby Children's HospitalCharlotte, North Carolina, United StatesNot Yet Recruiting
Doernbecher Children's HospitalPortland, Oregon, United StatesRecruiting

+ 12 more locations — full list on the registry record.

Follow this study

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Source record: clinicaltrials.gov/study/NCT05848687