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Study identifier: NCT05846399 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

CAT BITE Antibiotic Prophylaxis for the Hand/Forearm (CATBITE)

Condition: Cat Bite · Hand Injuries · Arm Injury  ·  Sponsor: University of Missouri-Columbia

PhasePhase 4
Planned participants72
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

Cat bites are puncture wounds that have the potential to seed bacteria deep within the joint capsule, periosteum, and bone. The hand is the most common site of bite injuries. Pasteurella multocida is the is the most common organism isolated from the mouths of cats that can cause infections after a bite. Prophylactic antibiotics are often recommended with amoxicillin-clavulanate for 3-5 days to decrease the incidence of developing an infection. However, only one randomized controlled clinical trial consisting of 12 patients has been performed to justify this course of treatment, raising the possibility that the use of antibiotics could be reduced or even eliminated. Investigators will compare different durations of prophylactic antibiotics and a placebo control for cat bites to the hand/forearm presenting to the Emergency Department, Urgent Care, Plastic Surgery Clinic using a randomized, controlled, double-blind clinical trial. Participants presenting to the University of Missouri Hospital Emergency Department, Missouri University (MU) Healthcare Urgent Care, Plastic Surgery Clinic over the next year will be offered the chance to enroll if they meet the inclusion/exclusion criteria. For inclusion, participants will be \>18 years of age, have cat bites to the hand or distal to elbow, and present within 24 hours of the cat bite injury. Participants must not present with active local or systemic infections, have received antibiotics within the past 30 days, or be immunocompromis…

This description comes directly from the study's public registry record.

Talk to the study team

Stephen H Colbert, MD  ·  573-882-2277  ·  ColbertS@health.missouri.edu

Kevin M Klifto, DO, PharmD  ·  573-882-2277  ·  kmkdg2@health.missouri.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of MissouriColumbia, Missouri, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05846399