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Study identifier: NCT05841472 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Anti-PD-1 Antibody Therapies of Camrelizumab in Combination With Pemetrexed and Carboplatin as First-line Treatment in Patients With Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

Condition: Non Squamous Non Small Cell Lung Cancer  ·  Sponsor: CrystalGenomics, Inc.

PhasePhase 2
Planned participants60
Who can joinAll sexes, 19 Years to 80 Years
Healthy volunteersNo

About this study

The objective of this bridging study is to acquire new drug approval in Korea for camrelizumab (SHR-1210), a drug that has already been approved in China for treatment in patients with histologically or cytologically confirmed advanced or metastatic (Stage IIIB-IV), EGFR/ALK wild-type, non-squamous, non-small cell lung cancer. In this study, subjects with advanced or metastatic, EGFR/ALK wild-type, non-squamous, non-small lung cancer will receive anti-PD-1 antibody therapy of camrelizumab in combination with pemetrexed + carboplatin as first-line treatment for at least 8 cycles (24 weeks). Then, the best overall RECIST responses (BOR) from subjects who have had at least 1 post-baseline tumor assessment will be evaluated to confirm that camrelizumab, a drug that has already been approved China, has similar efficacy in the Korean population as in the Chinese population.

This description comes directly from the study's public registry record.

Talk to the study team

Kyung Hye Kim  ·  +821087370206  ·  khkim@cgxinc.com

Always discuss trial participation with your own doctor first.

Locations (8)

Korea University Anam HospitalAnam, South KoreaRecruiting
Hallym University Sacred Heart HospitalAnyang, South KoreaRecruiting
Chonnam National University Hwasun HospitalHwasun, South KoreaRecruiting
Catholic University of Korea EunPyeong St. Mary's HospitalSeoul, South KoreaRecruiting
Catholic University of Korea Yeouido St. Mary's HospitalSeoul, South KoreaRecruiting
Korea University Guro HospitalSeoul, South KoreaRecruiting
Seoul Asan HospitalSeoul, South KoreaRecruiting
Busan National University Hospital YangsanYangsan, South KoreaRecruiting

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Source record: clinicaltrials.gov/study/NCT05841472