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Study identifier: NCT05840887 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Knee Osteotomy Associated With Allograft Meniscus Transplantation

Condition: Malalignment, Bone · Osteoarthritis, Knee  ·  Sponsor: Istituto Ortopedico Rizzoli

PhaseNA
Planned participants52
Who can joinAll sexes, 20 Years to 60 Years
Healthy volunteersNo

About this study

This is a prospective randomized double-blind controlled clinical trial with parallel arms and 1:1 allocation. The main objective of the BIOMAT project is to demonstrate, through an RCT, whether the combined approach by knee osteotomy and MAT can provide clinical improvement over knee osteotomy alone for the treatment of patients with monocompartmental knee OA associated with meniscal insufficiency and lower extremity malalignment. Secondary objectives are to demonstrate whether the addition of MAT to knee osteotomy in patients with monocompartmental OA can improve biomechanical parameters and whether this treatment has protective effects on the joint environment and cartilage degeneration.

This description comes directly from the study's public registry record.

Talk to the study team

Alessandro Di Martino, MD  ·  6366567  ·  roberta.licciardi@ior.it

Roberta Licciardi, MSc  ·  6366567  ·  roberta.licciardi@ior.it

Always discuss trial participation with your own doctor first.

Locations (1)

Istituto Ortopedico RizzoliBologna, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT05840887