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Study identifier: NCT05840354 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

RTMS and Steroid Joint Steroid Injection in Chronic Spinal Pain

Condition: Chronic Spinal Pain  ·  Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

PhaseNA
Planned participants40
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Chronic spinal pain (CSP) is one of the most common chronic pain conditions globally. Steroid joint injections (SJI) are a routine treatment option for patients with CLBP that is recalcitrant to other treatments. However, SJI has been shown to have limited long-term efficacy with patients often requiring another injection within months to adequately control pain. One option to prolong the analgesic effects of SJI is to use a type of noninvasive brain stimulation called repetitive transcranial magnetic stimulation (rTMS). Previous studies have shown rTMS may be capable of providing long-term pain relief in patients with chronic back pain. However, the literature on rTMS in patients with CSP is limited and no study has explored rTMS in patients receiving recurrent SJI for pain control. In this pilot randomized controlled trial study, we'll be investigating if combining rTMS with SJI in CSP individuals will enhance or prolong the analgesic effects of SJI alone. The investigators hypothesize that a combined rTMS and SJI intervention will be feasible, tolerable, and safe and will have larger and longer-lasting effects on CSP than a sham rTMS and SJI intervention.

This description comes directly from the study's public registry record.

Talk to the study team

Alexandria Roa Agudelo, MLA  ·  519-646-6100  ·  alexandria.roaagudelo@sjhc.london.on.ca

Keaton Lightfoot, BSc  ·  519-646-6100  ·  Keaton.Lightfoot@sjhc.london.on.ca

Always discuss trial participation with your own doctor first.

Locations (2)

St. Joseph's Health Care LondonLondon, Ontario, CanadaRecruiting
Parkwood Institute (Main Building)London, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT05840354