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Study identifier: NCT05839730 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Fast Induced Remodeling in Heart Failure With Preserved Ejection Fraction

Condition: Heart Failure With Preserved Ejection Fraction · Concentric Hypertrophy  ·  Sponsor: Medtronic Cardiac Rhythm and Heart Failure

PhaseNA
Planned participants105
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

FIRE-HFpEF is a multi-center, prospective, randomized, single-blinded, clinical feasibility study. This study will enroll up to 105 subjects with heart failure with preserved ejection fraction in the United States. Data will be collected to evaluate whether pacing therapies can lead to improvements in exercise capacity and health status of subjects.

This description comes directly from the study's public registry record.

Talk to the study team

Scott A Sarazin  ·  763-526-2817  ·  scott.a.sarazin@medtronic.com

Always discuss trial participation with your own doctor first.

Locations (8)

NCH Heart InstituteNaples, Florida, United StatesRecruiting
Prairie Education and Research Cooperative-St. Elizabeth'sO'Fallon, Illinois, United StatesRecruiting
Prairie Education and Research Cooperative-St. John'sSpringfield, Illinois, United StatesRecruiting
University of Kansas Medical CenterKansas City, Kansas, United StatesRecruiting
Duke UniversityDurham, North Carolina, United StatesRecruiting
Oklahoma Heart HospitalOklahoma City, Oklahoma, United StatesRecruiting
Houston Methodist Research InstituteHouston, Texas, United StatesRecruiting
The University of Vermont Medical CenterBurlington, Vermont, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05839730