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Study identifier: NCT05839717 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Determination of the Clonality Profile in Myeloproliferative Neoplasms and Association With the Thrombotic Complications (CLOJAK)

Condition: Myeloproliferative Neoplasm  ·  Sponsor: University Hospital, Bordeaux

PhaseN/A
Planned participants120
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Myeloproliferative Neoplasms (MPN) are associated with an increased risk of thrombosis. Platelets, red blood cells (RBC), leukocytes and endothelial cells are involved in these complications. An association with the JAK2V617F allele burden assessed in leukocytes has also been suggested. In some patients the allele burden measured in platelets and red blood cells is higher than the one determined in leukocytes. Our project aims at associating the risk of thrombosis with the allele burden determined in the cell populations (platelets, red blood cells, granulocytes and endothelial cells) and identifying high-risk clonality profiles.

This description comes directly from the study's public registry record.

Talk to the study team

Olivier MANSIER  ·  05 56 79 56 79  ·  olivier.mansier@chu-bordeaux.fr

Always discuss trial participation with your own doctor first.

Locations (11)

CHU d'Angers, Service Maladies du SangAngers, FranceRecruiting
CH de Bayonne, Service Hématologie CliniqueBayonne, FranceRecruiting
CHU de Bordeaux, Service Médecine Interne et Maladies InfectieusesBordeaux, FranceRecruiting
Institut Bergonié, Service Hématologie CliniqueBordeaux, FranceRecruiting
CHU de Brest, Service Hématologie CliniqueBrest, FranceRecruiting
CH de Dax, Service Hématologie CliniqueDax, FranceRecruiting
CH de Libourne, Service Hématologie CliniqueLibourne, FranceRecruiting
CH de Mont de Marsan, Service OncologieMont-de-Marsan, FranceRecruiting
CHU de Bordeaux, Service Hématologie BiologiePessac, FranceRecruiting
CHU de Bordeaux, Service Hématologie Clinique et Thérapie CellulairePessac, FranceRecruiting
CHU de Bordeaux, Service Médecine InternePessac, FranceNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT05839717