Condition: Carotid Atherosclerosis · Asymptomatic Carotid Artery Stenosis · Carotid Artery Atheroma · Sponsor: Washington University School of Medicine
The goal of this observational study is to learn more about plaque biology in asymptomatic carotid artery stenosis (ACAS) patients through imaging. The main questions it aims to answer are: * To determine the ability of 64Cu-CANF-Comb positron emission tomography (PET) to risk stratify ACAS patients for stroke event, to include transient ischemic attack or remote ipsilateral intervention. * To further understand the role of Natriuretic Peptide Receptor C (NPRC) in the evolution of carotid atherosclerosis. Participants will be asked to undergo a carotid PET-magnetic resonance imaging (MRI) examination to assess whether the carotid atherosclerosis uptake of 64Cu-CANF-Comb as measured by PET-MRI correlates with patient outcomes (stroke, transient ischemic attack, or remote ipsilateral intervention).
This description comes directly from the study's public registry record.
Molly Mohrman · 314-747-4633 · mohrmanm@wustl.edu
Pamela Woodard, MD · 314-362-7100 · woodardp@wustl.edu
Always discuss trial participation with your own doctor first.
| Cedars Sinai Medical Center | Los Angeles, California, United States | Recruiting |
| Washington University in St. Louis | St Louis, Missouri, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05838547