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Study identifier: NCT05838066 Synced from ClinicalTrials.gov · July 28, 2026
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Efficacy and Safety of KN026 in Combination With HB1801 in the First-line Treatment of Subjects With HER2-positive Recurrent or Metastatic Breast Cancer.

Condition: First-line Treatment of HER2-positive Recurrent or Metastatic Breast Cancer  ·  Sponsor: Shanghai JMT-Bio Inc.

PhasePhase 3
Planned participants880
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a randomized, controlled, open-label, multicenter, phase Ш clinical study designed to compare the efficacy and safety of KN026 in combination with HB1801 to trastuzumab in combination with pertuzumab and docetaxel in the first-line treatment of subjects with HER2-positive recurrent or metastatic breast cancer. The statistical assumption for this study is superiority. The primary study endpoint was PFS as assessed by Blinded Independ Review Committee (BIRC).

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Trials Information Group Officer  ·  +86-0311-69085587  ·  ctr-contact@mail.ecspc.com

fenglin She  ·  18301190515  ·  shefenglin@cspc.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Clinical Trials Information GroupBeijing, chaoyang, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05838066