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Study identifier: NCT05828810 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

CLinical Evaluation of ANtiseptic Skin Preparation in Revision Total Joint Arthroplasty of the Hip and Knee

Condition: Revision Total Hip Arthroplasty (RTHA) · Revision Total Knee Arthroplasty  ·  Sponsor: Sunnybrook Health Sciences Centre

PhaseNA
Planned participants400
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to compare two types of skin preparation solutions (chlorhexidine gluconate-alcohol solution and povidone-iodine solution) that help eliminate harmful bacteria on the skin at the time of surgery for patients having revision arthroplasty surgery of the hip or knee. The main outcome of interest for the definitive study is the need for re-operation for a wound complication or an infection of the prosthetic joint within one year after surgery. For the pilot trial, our main interest is to determine feasibility of a definitive trial. Feasibility outcomes will include: ability to recruit patients, ability to randomize patients, ability to collect complete data, estimate the event rate of our primary outcome, ability to carry out data linkages and determine the accuracy of collected data. Participants will be contacted at two time points after surgery to complete a 5-minute survey: after 30 days, and after 1 year.

This description comes directly from the study's public registry record.

Talk to the study team

Erin Lillie, MSc  ·  (437) 227-4458  ·  CLEANJoint@sunnybrook.ca

Always discuss trial participation with your own doctor first.

Locations (3)

Royal Victoria Regional Health CentreBarrie, Ontario, CanadaActive Not Recruiting
Health Sciences NorthGreater Sudbury, Ontario, CanadaRecruiting
Sunnybrook Holland CentreToronto, Ontario, CanadaActive Not Recruiting

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Source record: clinicaltrials.gov/study/NCT05828810