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Study identifier: NCT05828459 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

First-in-human Study of OT-A201 in Patients With Selected Hematological Malignancies and Solid Tumors

Condition: Hematological Malignancy · Solid Tumor  ·  Sponsor: Onward Therapeutics

PhasePhase 1
Planned participants150
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This phase 1 study is aimed at establishing the safety basis of OT-A201 in the treatment of hematological malignancies and solid tumors. In the dose of escalation part it is to characterize the overall safety and tolerability profile and determine the recommended dose(s) of OT-A201 as monotherapy, and in various combination regimens. Preliminary information about anti-cancer activity will be further explored in the expansion part of the study.

This description comes directly from the study's public registry record.

Talk to the study team

Bruno Piccolella  ·  +33 6 12 97 73 68  ·  bruno.piccolella@onward-therapeutics.com

Erica Wang  ·  +886 921 865 855  ·  erica.wang@onward-therapeutics.com

Always discuss trial participation with your own doctor first.

Locations (4)

ICM - MontpellierMontpellier, FranceRecruiting
Saint-Eloi Hospital - Montpellier (CHU)Montpellier, FranceRecruiting
Saint-Joseph Hospital - ParisParis, FranceRecruiting
Centre Eugène MarquisRennes, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT05828459