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Study identifier: NCT05824728 Synced from ClinicalTrials.gov · July 28, 2026
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Clinical Trial Evaluating the Efficacy and Safety of AGB101 for Treatment of Parkinson's Disease Related Psychosis

Condition: Parkinson Disease Psychosis  ·  Sponsor: Johns Hopkins University

PhasePhase 2
Planned participants30
Who can joinAll sexes, 40 Years to 85 Years
Healthy volunteersNo

About this study

This clinical trial will test whether AGB101 (low-dose levetiracetam, 220 mg, extended release tablet) can improve symptoms of psychosis in Parkinson's disease. Participants will be asked to complete up to 5 in-person study visits over approximately 20 weeks. Participants will receive both AGB101 and a placebo to take once a day for 6 weeks, with a 4-week washout in between. Participation will also involve physical/neurological exams, questionnaires, paper and pencil tests, providing blood and urine samples, and completing two MRI exams.

This description comes directly from the study's public registry record.

Talk to the study team

Caroline L Wagandt, BA  ·  410-955-5057  ·  cspeck1@jhmi.edu

Arnold Bakker, PhD  ·  410-502-6944  ·  abakker@jhu.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Johns HopkinsBaltimore, Maryland, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05824728