Condition: Acute Pain · Sponsor: University Hospital, Basel, Switzerland
This study is to investigate the effect of open-label placebo (OLP) application on acute pain in an experimental model of acute pain (simulating wound pain: this installation will apply monophasic, rectangular electrical pulses of 0.5ms duration with alternating polarity at 2 Hz frequency. The current will be increased to target a pain rating of 6 of 10 on the NRS (0 = no pain, 10 = worst imaginable pain). Three further adjustments in current will be made every 5 minutes for the next 15 minutes to compensate for habituation. This final current will be kept constant until the end of the particular experiment). In Part 1 duration of OLP analgesia will be examined, and onset and size of the effect will be reevaluated. In Part 2 of this study outcomes between subjects receiving one OLP injection, subjects receiving one repetition of the injection on a fixed time point and subjects receiving one repetition of the injection on-demand will be evaluated
This description comes directly from the study's public registry record.
Tobias Schneider, MD · +41 61 328 65 43 · tobias.schneider@usb.ch
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| University Hospital of Basel (USB); Department of Anaesthesiology | Basel, Switzerland | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05819476