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Study identifier: NCT05818683 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of Pasritamig (JNJ-78278343) in Combination With Other Agents for Metastatic Prostate Cancer

Condition: Metastatic Castration-resistant Prostate Neoplasms · Metastatic Hormone-sensitive Prostate Cancer  ·  Sponsor: Janssen Research & Development, LLC

PhasePhase 1
Planned participants300
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to identify the recommended phase 2 regimen(s) RP2R(s) of pasritamig and combination regimens in Part 1 (dose escalation) and to determine safety at the putative RP2R(s) of pasritamig with the combination regimens in Part 2 (dose expansion).

This description comes directly from the study's public registry record.

Talk to the study team

Study Contact  ·  844-434-4210  ·  Participate-In-This-Study1@its.jnj.com

Always discuss trial participation with your own doctor first.

Locations (15)

Florida Cancer SpecialistsSarasota, Florida, United StatesRecruiting
Start MidwestGrand Rapids, Michigan, United StatesRecruiting
Washington University School Of MedicineSt Louis, Missouri, United StatesRecruiting
Perlmutter Cancer Center at NYU Langone BrooklynBrooklyn, New York, United StatesRecruiting
Laura & Isaac Perlmutter Cancer Center at NYU Langone Hospital - Long IslandMineola, New York, United StatesRecruiting
NYU Langone HealthNew York, New York, United StatesRecruiting
Sidney Kimmel Cancer Center - Jefferson HealthPhiladelphia, Pennsylvania, United StatesRecruiting
Icon Cancer Centre Kurralta ParkKurralta Park, AustraliaRecruiting
Macquarie UniversityMacquarie University, AustraliaRecruiting
Peter MacCallum Cancer CentreMelbourne, AustraliaRecruiting
Princess Alexandra HospitalWoolloongabba, AustraliaRecruiting
Hosp Univ Vall D HebronBarcelona, SpainRecruiting

+ 3 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05818683