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Study identifier: NCT05817903 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Axitinib Intensification Plus Nivolumab or Nivolumab Alone After Nivolumab Plus Ipilimumab in mRCC Patients

Condition: Metastatic Renal Cell Carcinoma  ·  Sponsor: Consorzio Oncotech

PhasePhase 2
Planned participants118
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This phase II open label trial randomized patients who completed the induction with nivolumab plus ipilimumab without complete response or progressive disease will be randomized 1:1 to receive axitinib in addition to nivolumab (Arm A) or continue with nivolumab alone (Arm B).Treatment will be continued until progression of disease, unacceptable toxicity, patient's refusal, or physician decision whichever occurred first.

This description comes directly from the study's public registry record.

Talk to the study team

Roberto Iacovelli, MD  ·  +393339516295  ·  roberto.iacovelli@policlinicogemelli.it

Axin Service  ·  axin@oncotech.org

Always discuss trial participation with your own doctor first.

Locations (23)

ASST degli Spedali Civili di BresciaBrescia, ItalyNot Yet Recruiting
Istituto di Candiolo - Fondazione del Piemonte per l'Oncologia - IRCCSCandiolo, ItalyNot Yet Recruiting
Azienda Ospedaliera per l'emergenza CannizzaroCatania, ItalyNot Yet Recruiting
ASST di CremonaCremona, ItalyNot Yet Recruiting
Azienda Ospedaliero Universitaria CareggiFlorence, ItalyNot Yet Recruiting
Ospedale Policlinico San MartinoGenova, ItalyNot Yet Recruiting
Fondazione IRCCS - Istituto Nazionale dei TumoriMilan, ItalyNot Yet Recruiting
Istituto Europeo di Oncologia - IEOMilan, ItalyNot Yet Recruiting
A.O.U. Policlinico di ModenaModena, ItalyNot Yet Recruiting
Policlinico Duilio Casula - Azienda Ospedaliero-Universitaria di CagliariMonserrato, ItalyNot Yet Recruiting
Azienda Ospedaliero-Universitaria Maggiore della CaritàNovara, ItalyNot Yet Recruiting
Istituto Oncologico VenetoPadova, ItalyRecruiting

+ 11 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05817903