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Study identifier: NCT05817214 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Cadonilimab Plus Anlotinib for R/M/P Cervical Cancer

Condition: Cervical Cancer  ·  Sponsor: Zhongnan Hospital

PhasePhase 2
Planned participants35
Who can joinFemale, 18 Years to 75 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to test a new treatment combination including cadonilimab, anlotinib and granulocyte-macrophage colony-stimulating factor (GM-CSF) in recurrent, metastasis and persistent cervical cancer. The main questions it aims to answer are: * The efficacy of this combination in R/M/P CC; * The tolerance of this combination in R/M/P CC; * Possible biomarker of treatment response for this combination. Participants will receive cadonilimab of 10mg/kg every three weeks at day 1, take anlotinib (12mg) orally in day 1 to day 14, then take a 7 days break and subcutaneously injection of GM-CSF (200ug) from day 1 to day 14, then also take a 7-days break. This treatment will continue until progression or intolerable toxicity or withdraw of participants and it will last for no longer than 2 years.

This description comes directly from the study's public registry record.

Talk to the study team

Shaoxing Sun, M.D.  ·  +08613871286154  ·  sunshaoxing@whu.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Zhongnan Hospital of Wuhan UniversityWuhan, Hubei, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05817214